2-Benzyl-1,2,5-thiadiazolidine 1,1-dioxide → HCID 19774173, compound

HRID 1613638Notes

Reaction equation

HRID 1613638 reaction equation
[ClH:1].[CH2:2]([N:9]1[S:13](=[O:15])(=[O:14])[N:12]([C:16]2[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=2)[CH2:11][CH2:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C([N:30]1CCNS1(=O)=O)C1C=CC=CC=1>>[ClH:1].[CH2:2]([N:9]1[S:13](=[O:15])(=[O:14])[N:12]([C:16]2[CH:17]=[CH:18][C:19]([NH:20][NH2:30])=[CH:21][CH:22]=2)[CH2:11][CH2:10]1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 103758902-Benzyl-1,2,5-thiadiazolidine 1,1-dioxideHCID 19774182HCID 19774182, compound

Product 1

HCID 19774173HCID 19774173, compound

Procedure

The title compound was prepared from 4-(5-benzyl-1,1-dioxo-1,2,5-thiadiazolidin-2-yl)aniline hydrochloride by a similar method to that described for Intermediate 1 (step 1); pale brown solid; δH (250 MHz, DMSO-d6) 7.42-7.32 (5H, m, Ph), 7.24 (2H, d, J=8.5 Hz, Ar--H), 7.02 (2H, d, J=8.5 Hz, Ar--H), 4.24 (2H, s, PhCH2 --), 3.68 (2H, t, J=6.4 Hz, --CH2 --), 3.39 (2H, t, J=6.4 Hz, --CH2 --).

Sources & evidence

ORD record
ord-61d89b56e7bf43b68c9d231172125355
Source dataset
uspto-grants-1993_03
Patent number
US05194440

Reaction notes

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