4-Fluorobenzaldehyde → 4-{2-[Methyl(pyridin-2-yl)amino]ethoxy}benzaldehyde
Reaction equation
[CH3:1][N:2]([CH2:9][CH2:10][OH:11])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.F[C:13]1[CH:20]=[CH:19][C:16]([CH:17]=[O:18])=[CH:15][CH:14]=1>>[CH3:1][N:2]([CH2:9][CH2:10][O:11][C:13]1[CH:20]=[CH:19][C:16]([CH:17]=[O:18])=[CH:15][CH:14]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1Participants
3
Procedure
The title compound was prepared from 2-(N-methyl-N-(2-pyridyl)amino)ethanol (8.9 g) and 4-fluorobenzaldehyde by a similar procedure to that described in Preparation 22.
Workup
- customthat described in Preparation 22
Sources & evidence
- ORD record
- ord-5ae08263c57f418f9baa022a4aa2b540
- Source dataset
- uspto-grants-1993_03
- Patent number
- US05194443
Reaction notes
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