3-Phenylphenol → Phenylacetonitrile

HRID 1613798Notes

Reaction equation

HRID 1613798 reaction equation
[C:1]1([C:7]2[CH:8]=[C:9]([OH:13])[CH:10]=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[S:15]([N:18]=[C:19]=O)(=[O:17])=[O:16]>C1(C)C=CC=CC=1>[C:1]1([C:7]2[CH:8]=[C:9]([O:13][S:15](=[O:17])(=[O:16])[NH2:18])[CH:10]=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1.[C:1]1([CH2:7][C:19]#[N:18])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 2

HCID 113813-PhenylphenolHCID 70918Chlorosulfonyl isocyanate

Product 2

HCID 8794PhenylacetonitrileHCID 54439888HCID 54439888, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Using the procedure described in Example 84, the title compound was prepared from 17.0 g (0.010 mole) of 3-phenyphenol and 9.1 ml (0.105 mole) of chlorosulfonyl isocyanate in 100 ml of toluene to obtain 19.0 g (77%) of white flakes, mp 197°-199° C. (benzene-acetonitrile)

Sources & evidence

ORD record
ord-1b06a41112d9459cbe49c652267f9f76
Source dataset
uspto-grants-1993_03
Patent number
US05194446

Reaction notes

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