Diethyl Ether → Lithium, 1H-inden-1-yl-

HRID 1613832Notes

Reaction equation

HRID 1613832 reaction equation
C(OCC)C.[CH2:6]([Li:10])[CH2:7][CH2:8][CH3:9].[CH3:11][CH2:12][CH2:13][CH2:14][CH2:15]C>>[CH-:6]1[C:15]2[C:9](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:8]=[CH:7]1.[Li+:10]

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 8058HexaneHCID 178418339Butyllithium

Product 1

HCID 11116044Lithium, 1H-inden-1-yl-

Procedure

A 100 mL Schlenk flask is charged with diethyl ether, 50 mL, and n-butyllithium, 5.2 mL (13.88 mmole of a 2.68 M solution in hexane) at -78° C. To the magnetically stirred, chilled solution is added nitrogen degassed indene, 1.8 mL (15.27 mmole). The mixture is stirred and warmed to room temperature over 1 to 2 hours. The mixture is stirred at least an additional 4 hours at room temperature to insure complete reaction prior to further use.

Workup

  1. temperaturechilled solution
  2. additionis added nitrogen
  3. customdegassed indene, 1.8 mL (15.27 mmole)
  4. stirringThe mixture is stirred
  5. stirringThe mixture is stirred at least an additional 4 hours at room temperature
  6. customreaction

Sources & evidence

ORD record
ord-d436d126a1fe4451a3d28025b60fdaef
Source dataset
uspto-grants-1993_03
Patent number
US05194532

Reaction notes

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