Diethyl Ether → Lithium, 1H-inden-1-yl-

HRID 1613836Notes

Reaction equation

HRID 1613836 reaction equation
C(OCC)C.[CH2:6]([Li:10])[CH2:7][CH2:8][CH3:9].[CH3:11][CH2:12][CH2:13][CH2:14][CH2:15]C>>[CH-:6]1[C:15]2[C:9](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:8]=[CH:7]1.[Li+:10]

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 8058HexaneHCID 178418339Butyllithium

Product 1

HCID 11116044Lithium, 1H-inden-1-yl-

Procedure

A 100 mL Schlenk flask is charged with diethyl ether, 50 mL, and n-butyllithium, 5.22 mL (14.67 mmole) of a 2.81 M solution in hexane, at -78° C. To the magnetically stirred, chilled solution is added nitrogen degassed indene, 1.70 g (14.6 mmole). The mixture is stirred and warmed to room temperature over 1 to 2 hours. The solution is stirred at least an additional 4 hours at room temperature to insure complete reaction prior to further use.

Workup

  1. temperaturechilled solution
  2. additionis added nitrogen
  3. customdegassed indene, 1.70 g (14.6 mmole)
  4. stirringThe mixture is stirred
  5. stirringThe solution is stirred at least an additional 4 hours at room temperature
  6. customreaction

Sources & evidence

ORD record
ord-3b191807307e4a5fb40b532f8f61966d
Source dataset
uspto-grants-1993_03
Patent number
US05194532

Reaction notes

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