HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-(7-Methoxynaphthalen-1-yl)acetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-(7-Methoxynaphthalen-1-yl)acetic acid | HCID 13570105 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-(7-Methoxynaphthalen-1-yl)acetyl chloride | HCID 19385766 | — |
Reaction Steps
The (7-methoxynaphth-1-yl)acetic acid obtained above is dissolved by heating in 300 ml of chloroform. The mixture is heated under reflux, and then thionyl chloride is added dropwise. The mixture is refluxed for two hours and evaporated to dryness. An oil is obtained which crystallizes on cooling. The residue obtained is used as such in the following stage.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194614 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-2eefadc276a84559a247e66c8340f6b5 |
| Source note | uspto-grants-1993_03 |