HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl trichloroacetate → HCID 86746643, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl trichloroacetate | HCID 10588 | — |
| Reactant | HCID 15126712 | HCID 15126712 | — |
| Reactant | Diethyl aluminum chloride | HCID 16686102 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Toluene acetone | HCID 20247278 | — |
| Product | HCID 86746643 | HCID 86746643 | — |
Reaction Steps
Using the procedure of Example 18, 3,3-ethylenedioxy-9α-hydroxy-16β-methylandrost-5-en-17-one (3.60 g) was reacted with ethyl trichloroacetate (2.78 ml) in the presence of zinc dust (2.83 g) and diethylaluminium chloride (20 ml, 1M in hexane). Chromatography (silica gel, toluene/acetone 3/1) of the crude product (3.0 g) afforded the title compound as a single isomer.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194602 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-8250c1b8d5ec48cda16fe962fb0cfa07 |
| Source note | uspto-grants-1993_03 |