3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one → 1-[7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(2-{4-amino-3-chloro-5-fluorophenyl}-ethyl)-amino]-propane

HRID 161398Notes

Reaction equation

HRID 161398 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([cH:17][c:18]1[O:19][CH3:20])[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14][Cl:15])[CH2:10][CH2:11]2.[CH3:21][NH:22][CH2:23][CH2:24][c:25]1[cH:26][c:27]([Cl:33])[c:28]([NH2:32])[c:29]([F:31])[cH:30]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([cH:17][c:18]1[O:19][CH3:20])[CH2:7][C:8](=[O:16])[N:9]([CH2:12][CH2:13][CH2:14][N:22]([CH3:21])[CH2:23][CH2:24][c:25]1[cH:26][c:27]([Cl:33])[c:28]([NH2:32])[c:29]([F:31])[cH:30]1)[CH2:10][CH2:11]2

Participants

3

Reactant 2

HCID 130925103-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-oneHCID 20433831N-methyl-N-[2-(4-amino-3-chloro-5-fluoro-phenyl)-ethyl]-amine

Product 1

HCID 204337201-[7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl]-3-[N-methyl-N-(2-{4-amino-3-chloro-5-fluorophenyl}-ethyl)-amino]-propane

Sources & evidence

ORD record
ord-eaba9b51e8db421f8a741a6474b29915
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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