反应详情

A flask equipped with a stirrer, thermoter, nitrogen gas tube and reflux condenser was charged with 20.0 g of bis(4-hydroxyphenyl)methane, 50.0 g of methylene chloride and 23.0 g of trimethylamine. To the flask was added 26.0 g of propargyl chloroformate dropwise over one hour and the mixture was allowed to react for 6 hours at 30° C. After the reaction, the reaction mixture was treated with methylene chloride-water mixture and the organic phase was separated followed by drying over magnesium sulfate overnight. After filtering, the filtrate was evaporated in a rotary evaporator. The resulting crystals were recrystallized to give the title compound melting at 60° C. at a yield of 93.6% of theory.

1. customA flask equipped with a stirrer
2. temperaturethermoter, nitrogen gas tube and reflux condenser
3. customto react for 6 hours at 30° C
4. customAfter the reaction
5. customthe organic phase was separated
6. dry with materialby drying over magnesium sulfate overnight
7. filtrationAfter filtering
8. customthe filtrate was evaporated in a rotary evaporator
9. customThe resulting crystals were recrystallized