HuagongsheHuagongshe Chemistry Print Report · For research reference only
Quinolinic Acid → 2,3-Piperidinedicarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Quinolinic Acid | HCID 1066 | — |
| Catalyst | Nickel aluminide | HCID 6336846 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 2,3-Piperidinedicarboxylic acid | HCID 1226 | — |
Reaction Steps
Dissolve pyridine-2,3-dicarboxylic acid (20 g, 120 mmol) in 0.5N aqueous sodium hydroxide (900 mL). Add nickel/aluminum powder (45 g) in portions over 3 hours. Stir for 4 days, filter off the catalyst to yield the title compound in clear solution. The resulting free amine is not isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194430 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-4ae1b8d90aed453fa680cafe417b52af |
| Source note | uspto-grants-1993_03 |