HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 4-Chloro-2-difluoromethoxyimino-3-oxobutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | Tert-butyl 2-difluoromethoxyimino-3-oxobutyrate | HCID 54363554 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-Chloro-2-difluoromethoxyimino-3-oxobutyric acid | HCID 53987919 | — |
Reaction Steps
To a solution of tert-butyl 2-difluoromethoxyimino-3-oxobutyrate (5.0 g) in acetic acid (5 ml) was added sulfuryl chloride (8.5 ml). The mixture was stirred at 60°-63° C. for 7 hours. The solvent was evaporated in vacuo to give 4-chloro-2-difluoromethoxyimino-3-oxobutyric acid (4.5 g) as a glassy mass.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194432 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-8601cfb2141b430dbbf173161b737673 |
| Source note | uspto-grants-1993_03 |