HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 1-(2-Chloroethyl)-3-methyl-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| Reactant | HCID 178428694 | HCID 178428694 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(2-Chloroethyl)-3-methyl-1H-pyrazole | HCID 13764853 | — |
| Product | HCID 178428694 | HCID 178428694 | — |
Reaction Steps
When an equivalent amount of 3-methylpyrazole is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19 using toluene as solvent, 2-(3-methyl-1H-pyrazol-1-yl)ethyl chloride is isolated after column chromatography (3-methylpyrazole, Aldrich, 36%, C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE034201 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-b0fe3f7f01f64109bc712912ccef2012 |
| Source note | uspto-grants-1993_03 |