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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1614102Generated: November 1, 2026

3,5-Dimethylpyrazole → 3,5-Dimethylpyrazole

https://huagongshe.com/reaction/1614102

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DimethylpyrazoleHCID 6210—
Reactant1,2-DibromoethaneHCID 7839—
Reactant1-Bromo-2-ChloroethaneHCID 7849—
SolventTetrahydrofuranHCID 8028—
Product3,5-DimethylpyrazoleHCID 6210—
Product1-(2-chloroethyl)-3,5-dimethyl-1H-pyrazoleHCID 1149979—

Reaction Steps

When an equivalent amount of 3,5-dimethylpyrazole is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19 using tetrahydrofuran as solvent, 2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl chloride is isolated after column chromatography (3,5-dimethylpyrazole, Aldrich, 24%, C).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE034201
Source datasetuspto-grants-1993_03
ORD IDord-34f2e8ea8d294d83a3379b0780931942
Source noteuspto-grants-1993_03