Hydrazine → 2-Hydrazino-6,7-dichloroquinoxaline

HRID 1614157Notes

Reaction equation

HRID 1614157 reaction equation
Cl[C:2]1[CH:11]=[N:10][C:9]2[C:4](=[CH:5][C:6]([Cl:13])=[C:7]([Cl:12])[CH:8]=2)[N:3]=1.[NH2:14][NH2:15]>CCO>[NH:14]([C:2]1[CH:11]=[N:10][C:9]2[C:4](=[CH:5][C:6]([Cl:13])=[C:7]([Cl:12])[CH:8]=2)[N:3]=1)[NH2:15]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 100369782,6,7-Trichloroquinoxaline

Product 1

HCID 117759752-Hydrazino-6,7-dichloroquinoxaline

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To the 2,6,7-trichloroquinoxaline was added anhydrous EtOH (500 ml) to give a brown solution. 5.0 g (156 mmol) anhydrous hydrazine were added dropwise under N2, turning the solution red immediately. The solution was heated at reflux for 1 hour, cooled and the resulting solid was collected. Recrystallization from 1500 ml 95% EtOH yielded 13.0 g of 2-hydrazino-6,7-dichloroquinoxaline.

Workup

  1. customto give a brown solution
  2. temperatureThe solution was heated
  3. temperatureat reflux for 1 hour
  4. temperaturecooled
  5. customthe resulting solid was collected
  6. customRecrystallization from 1500 ml 95% EtOH

Sources & evidence

ORD record
ord-b45ad47063184f7683816c9a47cb1e3e
Source dataset
uspto-grants-1993_03
Patent number
US05196421

Reaction notes

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