HCID 11457720, compound → HCID 19773326, compound

HRID 1614255Notes

Reaction equation

HRID 1614255 reaction equation
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][C:9](=O)[CH2:10]2)(=[O:3])[CH3:2].[ClH:16].[CH2:17]([NH2:23])[C:18]1[O:22][CH:21]=[CH:20][CH:19]=1>>[ClH:16].[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH2:7][CH2:8][CH:9]([NH:23][CH2:17][C:18]1[O:22][CH:21]=[CH:20][CH:19]=1)[CH2:10]2)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 11457720HCID 11457720, compoundHCID 148364565-Acetylamino-2-tetralone

Product 1

HCID 19773326HCID 19773326, compound

Procedure

Starting from 2.03 g (0.01 mol) of 5-acetylamino-2-tetralone and 4.0 g (0.03 mol) of furfurylaminehydrochloride the title compound is obtained analogously to Example 4.1.11 in a yield of 2.1 g (65.4% of theory) and with a melting point of 296° C., which does not change after recrystallisation from methanol/ether.

Sources & evidence

ORD record
ord-3a50caa087304efe92e434f99319d69f
Source dataset
uspto-grants-1993_03
Patent number
US05196454

Reaction notes

Loading…