Pyridine → N-(2-Acetyloxyethyl)-pyridinium Bromide

Participants

Reaction Steps

A solution of 100.0 grams (0.599 mol) of 2-bromoethyl acetate, 47.37 grams (0.599 mol) of pyridine and 300 milliters of acetonitrile was heated at reflux for 19 hours and then cooled, concentrated on a rotovap to an oil, heated in methyl ethyl ketone and then cooled. On prolonged standing, solid crystallized was collected and dried. The yield of product was 129.5 grams (87.85% of theory); mp=69°-74° C.

Provenance & Evidence