Methyl chloroformate → HCID 19773756, compound

HRID 1614356Notes

Reaction equation

HRID 1614356 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:12])[CH3:11])[C:5]=1[NH:13][C:14]([NH:16][CH:17]([CH2:19][CH3:20])[CH3:18])=[S:15])([CH3:3])[CH3:2].[CH3:21][O:22][C:23]([Cl:25])=[O:24]>CC(C)=O>[ClH:25].[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:12])[CH3:11])[C:5]=1[NH:13][C:14](=[N:16][CH:17]([CH2:19][CH3:20])[CH3:18])[S:15][C:23]([O:22][CH3:21])=[O:24])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 6586Methyl chloroformateHCID 19773755HCID 19773755, compound

Product 1

HCID 19773756HCID 19773756, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

8.8 g of N-(2,6-diisopropylphenyl)-N'-sec.-butylthiourea are dissolved in 50 ml of acetone, and 3.78 g of chloroformic acid methyl ester are added thereto while stirring. The reaction mixture is stirred for a further 3 hours and then left to stand at room temperature for 10 hours. The product which crystallises out is filtered off-with suction and dried. The title compound of the formula ##STR6## is obtained in the form of colourless crystals; m.p. 136°-138° C. with decomposition.

Workup

  1. stirringThe reaction mixture is stirred for a further 3 hours
  2. waitleft
  3. customThe product which crystallises out
  4. filtrationis filtered off-with suction
  5. customdried

Sources & evidence

ORD record
ord-5e25190d509c4d50a575336e74f018fb
Source dataset
uspto-grants-1993_03
Patent number
US05196563

Reaction notes

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