反应详情

1500 mg of the diacetylene compound obtained were then dissolved in 300 ml of benzene, and 600 mg of potassium hydroxide, which were finely ground, was then added to the reaction mixture, followed by reflux under heating for 30 minutes. After filtration, the solvent was evaporated, and the residue was then purified by silica-gel chromatrgaphy using hexane as an eluent to obtain 1150 mg of 1-(4-methoxyphenyl)-1,3-butadiyne. This compound was a slightly yellowish white crystal.

1. additionwas then added to the reaction mixture
2. temperatureby reflux
3. temperatureunder heating for 30 minutes
4. filtrationAfter filtration
5. customthe solvent was evaporated
6. customthe residue was then purified by silica-gel chromatrgaphy