反应详情

800 mg of the thus-obtained diacetylene compound were dissolved in 200 ml of benzene, and 300 mg of potassium hydroxide were added to the reaction mixture, followed by reflux under heating for 15 minutes. After filtration, the solvent was evaporated, and the residue was purified by silica-gel chromatography using as hexane as an eluent to obtain 430 mg of 1-(3-methoxyphenyl)-1,3-butadiyne.

1. temperatureby reflux
2. temperatureunder heating for 15 minutes
3. filtrationAfter filtration
4. customthe solvent was evaporated
5. customthe residue was purified by silica-gel chromatography