Sulfuric Acid → 4-tert-Butylcyclohexanol

Participants

Reaction Conditions

Reaction Steps

A mixture consisting of 0.52 g (0.0039 mole) of diethylene glycol monoethyl ether and 5 ml of xylene was added dropwise to a mixture consisting of 0.65 g (0.017 mole) of sodium borohydride, 10 ml of xylene and 10 g (0.065 mole) of 4-t-butylcyclohexanone at 95° C. over 30 minutes while agitating the mixture. Subsequently, the mixture was agitated for one hour while maintaining it at 95° C. Next, after the mixture was cooled to room temperature, it was neutralized with dilute sulfuric acid. As a result, 4-t-butylcyclohexanol was quantitatively obtained.

Provenance & Evidence