Diethyl Ether → HCID 67855005, compound

Participants

Reaction Steps

A solution of 13.6 grams (0.044 mole) of 5-bromomethyl-4-cyano-1-(3-chloro-5-trifluoromethylpyridin-2-yl)-1H-pyrazole in 41 mL of pyridine was stirred at ambient temperature for three hours. After this time, the reaction mixture was slurried in 350 mL of diethyl ether and filtered. The filter cake was washed with additional diethyl ether. The filter cake was dried, yielding 11.9 grams of 1-[4-cyano-2-(3-chloro-5-trifluoromethylpyridin-2-yl)-1H-pyrazol-5-ylmethyl]pyridinium bromide. The nmr spectrum was consistent with the proposed structure.

Provenance & Evidence