2-Chlorobenzenesulfonyl chloride → N-[5-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-pyridin-3-yl]-2-chloro-benze nesulfonamide
Reaction equation
[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[Cl:11])[cH:4][cH:5][cH:6][cH:7]1.[NH2:12][c:13]1[c:14]2[c:15]([n:16][cH:17][n:18]1)[n:19]([CH:31]([CH3:32])[CH3:33])[cH:20][c:21]2[C:22](=[O:23])[c:24]1[cH:25][n:26][cH:27][c:28]([NH2:30])[cH:29]1.[NH2:34][c:35]1[c:36]2[c:37]([C:38]([c:39]3[cH:40][c:41]([NH:42][S:43]([c:44]4[cH:45][c:46]([F:47])[cH:48][c:49]([F:50])[cH:51]4)(=[O:52])=[O:53])[cH:54][n:55][cH:56]3)=[O:57])[cH:58][n:59]([CH:60]([CH3:61])[CH3:62])[c:63]2[n:64][cH:65][n:66]1>>[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[NH:30][c:28]2[cH:27][n:26][cH:25][c:24]([C:22]([c:21]3[c:14]4[c:13]([NH2:12])[n:18][cH:17][n:16][c:15]4[n:19]([CH:31]([CH3:32])[CH3:33])[cH:20]3)=[O:23])[cH:29]2)[cH:4][cH:5][cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e399badc923a4eaf8d3d7267f32e1d56
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…