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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1614612Generated: October 25, 2026

1-Benzyl-3-benzoylpyrrolidine → 2-(4-Fluorobenzoyl)-1-(3-phenoxypropyl)pyrrolidine

https://huagongshe.com/reaction/1614612

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzyl-3-benzoylpyrrolidineHCID 19771946—
Reactant2-Cyano-1-(3-phenoxypropyl)pyrrolidineHCID 19771983—
ReactantHCID 178418676HCID 178418676—
Product2-(4-Fluorobenzoyl)-1-(3-phenoxypropyl)pyrrolidineHCID 19771970—

Reaction Steps

Following the procedure for the preparation of 1-benzyl-3-benzoylpyrrolidine (U.S. Pat. No. 3,479,370) the title compound is prepared from 2-cyano-1-(3-phenoxypropyl)pyrrolidine and 4-fluorophenylmagnesium bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05198449
Source datasetuspto-grants-1993_03
ORD IDord-7c57b97377f54d27be402d6029d14c35
Source noteuspto-grants-1993_03