Methyl Isocyanate → HCID 19772056, compound
Reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH:19][C:20]2[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=2)[CH:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][NH2:18])[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[CH3:27][N:28]=[C:29]=[O:30]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([NH:19][C:20]2[CH:21]=[CH:22][C:23]([F:26])=[CH:24][CH:25]=2)[CH:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][NH:18][C:29]([NH:28][CH3:27])=[O:30])[CH2:11][CH2:10]2)=[CH:6][CH:7]=1Participants
3
Procedure
The compound of Example 59 is reacted with methyl isocyanate in an aprotic solvent to obtain the title compound.
Sources & evidence
- ORD record
- ord-8422bca27c0549b1bff9ccca16d7d0c8
- Source dataset
- uspto-grants-1993_03
- Patent number
- US05198449
Reaction notes
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