Benzene, (3-bromopropoxy)- → HCID 19772005, compound

HRID 1614657Notes

Reaction equation

HRID 1614657 reaction equation
Cl.[F:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][CH:10]([C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)[CH:11]2[CH2:15][CH2:14][NH:13][CH2:12]2)=[CH:5][CH:4]=1.[O:23]([CH2:30][CH2:31][CH2:32]Br)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[F:2][C:3]1[CH:4]=[CH:5][C:6]([NH:9][CH:10]([C:16]2[CH:17]=[CH:18][C:19]([F:22])=[CH:20][CH:21]=2)[CH:11]2[CH2:15][CH2:14][N:13]([CH2:32][CH2:31][CH2:30][O:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:12]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 68522Benzene, (3-bromopropoxy)-HCID 19772002HCID 19772002, compound

Product 1

HCID 19772005HCID 19772005, compound

Procedure

The title compound is prepared from N,α-bis(4-fluorophenyl)-3-pyrrolidinemethanamine hydrochloride and 3-phenoxypropylbromide according to the procedure of Example 8.

Sources & evidence

ORD record
ord-88ab582a04f94959a56fced0dfe9faea
Source dataset
uspto-grants-1993_03
Patent number
US05198449

Reaction notes

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