Sodium Methoxide → HCID 10445008, compound

Participants

Reaction Steps

The product of stage c) (0.33 g, 0.9 mmol) was added to a solution of sodium methoxide (from 0.021 g, 0.9 mmol of sodium metal) in dry methanol (8 ml) and the mixture stirred at room temperature for 5 hours. The solution was neutralised with Dowex 50 (H+) resin, the resin filtered and washed with methanol (2×4 ml) and the combined filtrate and washings evaporated to dryness. The residue was washed with ether (2×5 ml) and recrystallised from acetonitrile to give pale yellow crystals of the title compound.

Provenance & Evidence