HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → 2-Chloro-5-(chloromethyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | 2-Chloro-5-methyl-pyridine | HCID 581393 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 2-Chloro-5-(chloromethyl)pyridine | HCID 155479 | 69% |
Reaction Steps
1 Mol of 2-chloro-5-methylpyridine and 128 g of acetonitrile are heated to reflux. The mixture is irradiated with UV light and chlorine gas is introduced in a slight excess. The reaction is terminated as soon as 0.37 mol of product has been formed. 0.46 Mol of starting material is simultaneously recovered. Based on the reacted starting material, a yield of 69% results.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05198549 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-bec3b7966f6848f8a9ef96e2708d32b3 |
| Source note | uspto-grants-1993_03 |