Triethylamine → HCID 13980930, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 40 g (0.153 mol) of 2-(4-fluorophenyl)-hexafluoro-2-propanol and 15.5 g (0.153 mol) of triethylamine in 75 ml of dry diethyl ether were added dropwise with stirring at a temperature of 25° C. to a solution of 18 g (0.166 mol) of α-fluoroacryloyl chloride (obtained according to Example 4) in 25 ml of dry diethyl ether in the course of 45 minutes. The reaction mixture was then stirred at a temperature of 25° C. for a further 2 hours. The resulting solid was filtered off. The filtrate was distilled under reduced pressure after addition of 0.01 g of hydroquinone monomethyl ether. 42.5 g (83 percent of theory) of 2-(4-fluorophenyl)-hexafluoro-2-propyl α-fluoroacrylate having a boiling point of 70° to 73° C. (under 0.5 mbar) were obtained.

Provenance & Evidence