HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dihydrocoumarin → 4-Hydroxy-1-indanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dihydrocoumarin | HCID 660 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | 4-Hydroxy-1-indanone | HCID 590547 | — |
Reaction Steps
4-Hydroxy-1-indanone (76) was synthesized by aluminum chloride induced re-cyclization of dihydrocumarin (75), according to Org. Lett., 2007, 9(15), p. 2915-2918. The reaction was performed on 100 g of (75) to furnish (76) with 85% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765738B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-dc58bf559fe642c3915b01f67f027b71 |
| Source note | uspto-grants-2014_07 |