Hydrogen Peroxide → HCID 66785983, compound

Participants

Reaction Steps

To a solution of 4-[5-(tert-butyldimethylsilanyloxy)-4-(tert-butyldimethylsilanyloxymethyl)-pentyl]pyridine (0.43 g) prepared in (4) in chloroform (5.0 mL) were added methyltrioxorhenium (VII) (0.0030 g) and aqueous 30% hydrogen peroxide (0.21 mL). The reaction mixture was stirred at RT for 4 hr. An appropriate amount of manganese dioxide (IV) was added to the reaction mixture. The mixture was stirred for 1 hr. Water was added to the mixture and the mixture was extracted with chloroform. The organic layer was dried over Na2SO4. The solvent was removed under reduced pressure to obtain the crude title compound.

Provenance & Evidence