Dimethyl Sulfoxide → 4-(4-Amino-2,3-difluorophenoxy)pyridine-2-carboxamide
Reaction equation
[CH3:21][C:22]([CH3:23])([O-:24])[CH3:25].[CH3:39][S:40](=[O:41])[CH3:42].[Cl:27][c:28]1[cH:29][c:30]([C:34](=[O:35])[NH2:36])[n:31][cH:32][cH:33]1.[K+:26].[NH2:11][c:12]1[c:13]([OH:14])[c:15]([F:16])[c:17]([F:18])[cH:19][cH:20]1.[NH2:1][c:2]1[c:3]([F:10])[c:4]([F:9])[c:5]([OH:8])[cH:6][cH:7]1.[Na+:38].[OH-:37]>>[NH2:1][c:2]1[c:3]([F:10])[c:4]([F:9])[c:5]([O:8][c:28]2[cH:29][c:30]([C:34](=[O:35])[NH2:36])[n:31][cH:32][cH:33]2)[cH:6][cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-65bef1402ba34b618592776a4289476e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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