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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1615233Generated: November 1, 2026

N-(2-Oxoindolin-6-yl)acetamide → HCID 178474026, compound

https://huagongshe.com/reaction/1615233

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-Oxoindolin-6-yl)acetamideHCID 2749839—
Reactant1H-Indazole-5-carboxaldehydeHCID 21250644—
ProductHCID 178474026HCID 178474026—

Reaction Steps

The title compound was synthesized according to the method described for Example A11B except substituting N-(2-oxoindolin-6-yl)acetamide (40 mg, 0.210 mmol) and 1H-indazole-5-carbaldehyde (34 mg, 0.231 mmol) to obtain 41 mg, 61%. 1H NMR (400 MHz, d6-DMSO) δ 13.31 (s, 1H), 10.55 (s, 1H), 10.07 (s, 1H), 8.19 (s, 1H), 8.15 (s, 1H), 7.71-7.64 (m, 2H), 7.61 (s, 1H), 7.57 (d, J=8.4 Hz, 1H), 7.48 (s, 1H), 6.89 (d, J=8.3 Hz, 1H), 2.04 (s, 3H); MS ESI 319.1 [M+H]+, calcd for [C18H14N4O2+H]+ 319.12.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765748B2
Source datasetuspto-grants-2014_07
ORD IDord-95a3b5cb5ee34cef82b06d781e026b6b
Source noteuspto-grants-2014_07