Reaction Steps
According to the method of Example A19, utilizing 6-(pyridin-3-yl)indolin-2-one (37.1 mg, 0.18 mmol) and 1H-benzo[d][1,2,3]triazole-5-carbaldehyde (25.8 mg, 0.18 mmol), the title compound was obtained as an orange solid (20 mg, 34%). 1H NMR (400 MHz, DMSO-d6) δ ppm 15.96 (br.s. 1H),10.83 (s, 1H), 8.86 (br. s., 1H), 8.57-8.61 (m, 1H), 8.45 (br. s., 0.5H), 8.18 (br. s., 1H), 8.05 (d, J=7.83 Hz, 1H), 7.95 (br. s., 1H), 7.86 (s, 0.5H), 7.75 (br. s., 1H), 7.64 (d, J=7.33 Hz, 1H), 7.49 (dd, J=7.71, 4.93 Hz, 1H), 7.22 (d, J=7.58 Hz, 1H), 7.17 (s, 1H); 1H NMR (400 MHz, DMF-d7) δ ppm 10.77 (br. s., 1H), 8.94 (br. s., 1H), 8.61-8.65 (m, 1H), 8.42 (s, 1H), 8.13 (t, J=7.96 Hz, 1H), 7.93 (s, 1H), 7.90 (d, J=8.84 Hz, 1H), 7.78 (d, J=7.83 Hz, 1H), 7.52 (dd, J=7.71, 4.67 Hz, 1H), 7.33 (s, 1H), 7.30 (d, J=7.83 Hz, 1H); MS ESI 340.1 (100) [M+H]+, calcd for [C20H13N5O+H]+340.4.
