1H-Indazole-5-carboxaldehyde → HCID 178516991, compound

Participants

Reaction Steps

According to the method of Example A19, utilizing 6-(pyridin-3-yl)indolin-2-one (25 mg, 0.12 mmol) and 1H-indazole-5-carbaldehyde (17.4 mg, 0.12 mmol), the title compound was obtained as an orange solid (7 mg, 17%). 1H NMR (400 MHz, DMSO-d6) δ ppm 13.32 (br. s., 1H), 10.81 (s, 1H), 9.04 (s, 1H), 8.89 (d, J=1.26 Hz, 1H), 8.57 (dd, J=4.55, 1.26 Hz, 1H), 8.52 (d, J=7.83 Hz, 1H), 8.25 (s, 1H), 8.06-8.11 (m, 1H), 8.04 (s, 1H), 7.87 (d, J=7.83 Hz, 1H), 7.62 (d, J=8.84 Hz, 1H), 7.49 (dd, J=7.33, 4.55 Hz, 1H), 7.38 (dd, J=7.83, 1.26 Hz, 1H), 7.11 (d, J=1.01 Hz, 1H); MS ESI 339.1 (100) [M+H]+, calcd for [C21H14N4O+H]+ 339.4.

Provenance & Evidence