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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1615240Generated: November 2, 2026

5-Bromo-2-oxindole → HCID 178517022, compound

https://huagongshe.com/reaction/1615240

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-oxindoleHCID 611193—
Reactant1H-Indazole-5-carboxaldehydeHCID 21250644—
ProductHCID 178517022HCID 17851702210.6%

Reaction Steps

The title compound was synthesized according to the method described for Example A11B except substituting 5-bromooxindole (40 mg, 0.189 mmol) and 1H-indazole-5-carbaldehyde (30 mg, 0.208 mmol) to obtain the title compound (6.8 mg, 4.0%) as a yellow solid. 1H NMR (400 MHz, CD3OD) δ 8.19 (s, 1H), 8.17 (s, 1H), 7.95 (s, 1H), 7.77 (s, 1H), 7.76-7.68 (m, 2H), 7.38 (d, J=8.59 Hz, 1H), 6.87 (d, J=8.59 Hz, 1H); MS ESI 340.1 [M+H]+, calcd for [C16H10BrN3O+H]+ 340.01.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765748B2
Source datasetuspto-grants-2014_07
ORD IDord-a005f086ae1f4e38a9c6be5e2647c7f6
Source noteuspto-grants-2014_07