N-Methyloxindole → HCID 178481479, compound

Participants

Reaction Steps

The title compound was synthesized according to the method described for Example A11B, except substituting 1-methylindolin-2-one (18 mg, 0.124 mmol) and 1H-benzo[d][1,2,3]triazole-6-carbaldehyde (20 mg, 0.136 mmol) and then purified by preparatory HPLC to obtain 3.4 mg, 10% of a yellow solid. 1H NMR (400 MHz, CD3OD) δ 8.23 (bs, 1H), 8.00 (bs, 1H), 7.95 (s, 1H), 7.84-7.75 (m, 1H), 7.59 (d, J=7.58 Hz, 1H), 7.34 (t, J=8.00 Hz, 1H), 7.04 (d, J=7.83 Hz, 1H), 6.92 (d, J=7.58 Hz, 1H), 3.35 (s, 3H); MS ESI 277.0 [M+H]+, calcd for [C16H12N4O+H]+ 277.11.

Provenance & Evidence