N-Methyloxindole → HCID 178481478, compound

Participants

Reaction Steps

The desired product was synthesized according to the method described for Example A11B, except substituting 1-methylindolin-2-one (37 mg, 0.249 mmol) and 1H-indazole-6-carbaldehyde (40 mg, 0.274 mmol) and then purified by preparatory HPLC to obtain the title compound (12 mg, 17%) as a yellow solid. 1H NMR (400 MHz, CD3OD) δ 8.13 (s, 1H), 7.96-7.86 (m, 3H), 7.67 (d, J=7.83 Hz, 1H), 7.46 (d, J=8.08 Hz, 1H), 7.33 (t, J=7.71 Hz, 1H), 7.02 (d, J=7.83 Hz, 1H), 6.93 (t, J=7.71 Hz, 1H), 3.31 (s, 3H); MS ESI 276.1 [M+H]+, calcd for [C17H13N3O+H]+ 276.11.

Provenance & Evidence