反应详情

The title compound was synthesized from 3-iodo-1H-indazole-6-carbaldehyde (15 mg, 0.0551 mmol) and oxindole (8 mg, 0.0616 mmol) according to the method described for Example A11B and purified by column chromatography (silica gel, CH2Cl2/MeOH, 98:2 to 96:4) to obtain 6.9 mg, 33% of a yellow solid. 1H NMR (400 MHz, CD3OD) δ 7.89-7.82 (m, 2H), 7.63-7.49 (m, 3H), 7.23 (t, J=8.21 Hz, 1H), 6.91 (d, J=7.07 Hz, 1H), 6.89-6.83 (m, 1H); MS ESI 388.0 [M+H]+, calcd for [C16H10IN3O+H]+ 387.99.

1. custompurified by column chromatography (silica gel, CH2Cl2/MeOH, 98:2 to 96:4)