Trifluoroacetic acid → HCID 178509211, compound

Participants

Reaction Steps

To a solution of (E)-tert-butyl 5-((2-oxoindolin-3-ylidene)methyl)-1H-indazol-3-ylcarbamate (14 mg, 0.04 mmol) in CH2Cl2 (1 mL) was added TFA (0.25 mL) and the reaction was stirred for 3 h. The solution was concentrated to dryness and purified by preparatory HPLC to give the title compound as a 3:2 mixture of E/Z isomers. ESI 277.0 [M+H]+, calcd for [C16H12N4O+H]+ 277.1.

Provenance & Evidence