1,3-Dihydro-2H-pyrrolo(2,3-b)pyridin-2-one → HCID 178517371, compound

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Reaction Steps

The title compound (50 mg, 95%) was synthesized as an orange solid according to the method described for Example A67 using 1H-pyrrolo[2,3-b]pyridin-2(3H)-one (26.8 mg, 0.2 mmol) and 1H-indazole-5-carbaldehyde (29.2 mg, 0.2 mmol). 1H NMR (400 MHz, DMSO-d6) δ 13.36 (s, 1H, NH), 11.20 (s, 1H, NH), 8.21 (s, 2H), 8.09 (d, J=5.2 Hz, 1H), 7.94 (d, J=8.0 Hz, 1H), 7.89 (s, 1H), 7.72 (d, J=8.8 Hz, 1H), 7.68 (d, J=8.4 Hz, 1H), 6.91 (dd, J=8.0 Hz, 5.6 Hz, 1H); MS ESI 263.0 [M+H]+, calcd for [C15H10N4O+H]+ 263.1.

Provenance & Evidence