5-Methylindolin-2-one → HCID 178422515, compound

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Reaction Steps

According to procedure for the synthesis of (E)-3-((3-((E)-2-(pyridin-4-yl)vinyl)-1H-indazol-6-yl)methylene)indolin-2-one, except substituting 5-methyloxindole (9 mg, 0.06 mmol) to give the title compound as an orange solid (5.9 mg, 26%). 1H NMR (400 MHz, d6-DMSO) δ 13.58 (br s, 1H), 10.53 (br s, 1H), 8.57 (br s, 2H), 8.36 (d, J=8.0 Hz, 1H), 7.93-7.46 (m, 8H), 7.06 (d, J=8.0 Hz, 1H), 6.79 (d, J=5.8 Hz, 1H), 2.16 (s, 3H); MS ESI 379.2 [M+H]+, calcd for [C24H18N4O+H]+ 379.15.

Provenance & Evidence