Oxindole → HCID 68753876, compound

Participants

Reaction Steps

According to the method of Example A19, indolin-2-one (17 mg, 0.13 mmol) and 3-cyclopropyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazole-6-carbaldehyde (40 mg, 0.13 mmol) were reacted to obtain crude product. The crude mixture was purified by prepTLC (SiO2 2% MeOH in DCM) to provide the title compound as a yellow solid (48 mg, 88%). MS ESI 432.2 [M+H]+, calcd for [C25H29N3O2Si+H]+ 432.6.

Provenance & Evidence