1-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrile → 4-[2-(Trans-4-aminocyclohexyl)ethyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbonitrile
Reaction equation
[C:1]([N:5]([C:2](=[O:3])[O-:4])[CH:9]1[CH2:10][CH2:11][CH:12]([CH2:15][CH2:16][N:17]2[C:18](=[O:29])[CH2:19][O:20][c:21]3[c:22]2[cH:23][c:24]([C:27]#[N:28])[cH:25][cH:26]3)[CH2:13][CH2:14]1)([CH3:6])([CH3:7])[CH3:8].[NH2:30][CH:31]1[CH2:32][CH2:33][N:34]([CH2:35][CH2:36][n:37]2[c:38]3[c:39]([cH:40][cH:41][c:42]([C:43]#[N:44])[cH:45]3)[cH:46][cH:47][c:48]2=[O:49])[CH2:50][CH2:51]1>>[NH2:5][CH:9]1[CH2:10][CH2:11][CH:12]([CH2:15][CH2:16][N:17]2[C:18](=[O:29])[CH2:19][O:20][c:21]3[c:22]2[cH:23][c:24]([C:27]#[N:28])[cH:25][cH:26]3)[CH2:13][CH2:14]1Participants
3
Sources & evidence
- ORD record
- ord-db8fb3f1d5154d919a1fedf22fe87fb8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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