tert-Butyl (2-oxoindolin-5-yl)carbamate → HCID 178452630、化合物

関与物質

反応手順

The title compound (102 mg, 76%) was synthesized as orange-yellow solid according to the method described for Example A11B from tert-butyl 2-oxoindolin-5-ylcarbamate (70 mg, 0.282 mmol) and (E)-3-(2-(pyridin-4-yl)vinyl)-1H-indazole-6-carbaldehyde (70 mg, 0.282 mmol). 1H NMR (400 MHz, d6-DMSO) δ 13.53 (s, 1H), 10.47 (s, 1H), 9.14 (s, 1H), 8.55 (d, J=6.5 Hz, 2H), 8.33 (d, J=8.8 Hz, 1H), 7.88-7.83 (m, 3H), 7.74 (s, 2H), 7.69 (d, J=6.5 Hz, 2H), 7.56-7.50 (m, 2H), 6.75 (d, J=8.2 Hz, 1H), 1.34 (s, 9H); MS ESI 480.3 [M+H]+, calcd for [C28H25N5O3+H]+ 480.20.

情報源と証拠