3-Chloro-4-methylphenylboronic acid → 1-(3-Chloro-4-methylphenyl)-4,5-difluoro-2-[4-(methylsulfonyl)phenyl]benzene
Reaction equation
[Br:1][c:2]1[c:3](-[c:10]2[cH:11][cH:12][c:13]([S:16](=[O:17])(=[O:18])[CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([F:9])[c:6]([F:8])[cH:7]1.[Cl:20][c:21]1[cH:22][c:23]([B:28]([OH:29])[OH:30])[cH:24][cH:25][c:26]1[CH3:27]>>[c:2]1(-[c:23]2[cH:22][c:21]([Cl:20])[c:26]([CH3:27])[cH:25][cH:24]2)[c:3](-[c:10]2[cH:11][cH:12][c:13]([S:16](=[O:17])(=[O:18])[CH3:19])[cH:14][cH:15]2)[cH:4][c:5]([F:9])[c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-a38a19128f434e9fb07183a7b3525e54
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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