m-Chloroperbenzoic acid → HCID 67204402, compound

Participants

Reaction Steps

1-(2-(Methylthio)pyrimidin-4-yl)-6-(3-nitrophenyl)-1H-indole (91 mg, 0.251 mmol) was dissolved in methylene chloride (1 mL). At 0° C., 3-chloroperoxybenzoic acid (87 mg, 0.502 mmol) was added. 1 hour later, the reaction mixture was added to sodium bicarbonate aqueous solution and extracted with methylene chloride. The combined organic layer was washed with brine, dried with magnesium sulfate, and concentrated under reduced pressure. 1-(2-(Methylsulfinyl)pyrimidin-4-yl)-6-(3-nitrophenyl)-1H-indole (102 mg) was yielded.

Provenance & Evidence