3-Carboxyphenylboronic acid → HCID 86680669, compound

Participants

Reaction Steps

This compound was prepared from tert-butyl 5-((diphenoxyphosphoryl)oxy)-2H-1,4-oxazine-4(3H)-carboxylate and 3-boronobenzoic acid using a procedure similar to that described in Example 2 (Steps 1-3a) above. The product was isolated as an off-white solid (26% yield); 1H-NMR (d6-DMSO) 1.01 (9H, s), 3.71 (2H, t), 4.12 (2H, t), 6.50 (1H, s), 7.40-7.46 (2H, m), 7.74-7.77 (2H, m), 12.94 (1H, brs); 13C-NMR (d6-DMSO) 27.7, 41.5, 66.8, 126.8, 128.0, 128.2, 130.1, 133.0; MS ES(+) 249.9 (M+-tBu). IR λmax=1694 cm−1.

Provenance & Evidence