4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide → HCID 86680670, compound

Participants

Reaction Steps

This compound was prepared from tert-butyl 5-((diphenoxyphosphoryl)oxy)-2H-1,4-oxazine-4(3H)-carboxylate and N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide using a procedure similar to that described in Example 2 (Steps 1-3a) above. The product was isolated as a white solid (44% yield); 1H-NMR (d6-DMSO) 1.07 (9H, s), 2.02 (3H, s), 3.66 (2H, t), 4.08 (2H, t), 6.32 (1H, s), 7.09 (2H, d), 7.49 (2H, d), 9.88 (1H, s); MS ES(+) 263.0 (M+-tBu); HRMS m/z calcd for C17H22N2O4+H+ 319.1658 [M+H+]. Found 319.1658. IR λmax=1694 cm−1.

Provenance & Evidence