5-Methoxypyridine-3-boronic Acid → HCID 86680678, compound

Participants

Reaction Steps

This compound was prepared from tert-butyl 5-((diphenoxyphosphoryl)oxy)-2H-1,4-oxazine-4(3H)-carboxylate and 5-methoxypyridin-3-ylboronic acid using a procedure similar to that described in Example 2 (Steps 1-3a) above. The product was isolated as a white solid (45% yield); 1H-NMR (d6-DMSO) 1.07 (9H, s), 3.70 (2H, t), 3.81 (3H, s), 4.12 (2H, t), 6.57 (1H, s), 7.14 (1H, m), 8.02 (1H, d), 8.11 (1H, d); MS ES(+) 293.3 (M++1); HRMS m/z calcd for C15H20N20O4+H+ 293.1501 [M+H+]. Found 293.1519. IR λmax=1701 cm−1.

Provenance & Evidence