4-Methoxycarbonylphenylboronic acid → HCID 70938355, compound

HRID 1615455Notes

Reaction equation

HRID 1615455 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][C@@H:6]2[OH:11].[CH3:12][O:13][C:14]([C:16]1[CH:21]=[CH:20][C:19](B(O)O)=[CH:18][CH:17]=1)=[O:15]>>[OH:11][C@@H:6]1[C:7]2[C:3](=[C:2]([O:1][C:19]3[CH:20]=[CH:21][C:16]([C:14]([O:13][CH3:12])=[O:15])=[CH:17][CH:18]=3)[CH:10]=[CH:9][CH:8]=2)[CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 27343694-Methoxycarbonylphenylboronic acidHCID 86672960201655-77-8

Product 1

HCID 70938355HCID 70938355, compoundYield 42.7%

Procedure

According to the method of (Example 99) <Step 1>, from (1S)-4-hydroxy-2,3-dihydro-1H-inden-1-ol (0.99 g) and (4-(methoxycarbonyl)phenyl)boronic acid (1.31 g) that are commercially available or are obtained according to a known method, the subject compound (0.80 g) was obtained as pale yellow solid.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-e2c40e49838f4e9ea4c01382f0985019
Source dataset
uspto-grants-2014_07
Patent number
US08765752B2

Reaction notes

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